Alaabta
Doxifluridine
Qaab-dhismeedka
Jireed
Muuqashada: Caddaan Adag
Cufnaanta: 1.3751 (qiyaas)
Meesha dhalaalaysa: 188-192 °c ( shid)
Wareegga Gaarka ah: d25 +18.4° (c = 0.419 Gudaha Biyaha)
Dib-u-celinta: 20 ° (c=1, H2o)
Xaaladda Kaydinta: Jawi aan toos ahayn, Heer kulka qolka
Qodobka aysiidhka (pka): 7.4 ( saacada 25 ℃ )
Xogta Badbaadada
Qaybta halista: Alaabo khatar ah maaha
Gaadiidka khatarta ah:
Qaybta baakadaha:
Codsiga
1. Sida dawada 5-Flurouridine.Pyrimidine nucleoside fluorinated leh oo leh waxqabad cytostatic ah.Si caafimaad ahaan loo isticmaalo kansarka caloosha, kansarka mindhicirka, kansarka naasaha, heerka cafiska wuxuu gaari karaa in ka badan 30%
2. Dhexdhexaad u ah dawooyinka ka hortagga Fluorouracil
Hordhac isticmaalka
1. Dawooyinka antitumor ee ku salaysan fluorouracil ayaa horudhac u ah fluorouracil.phosphorylase enzyme thymidine, kaas oo ku jira unugyada burooyinka, ayaa ku shaqeeya si uu ugu beddelo fluorouracil ee burada, sidaas darteed saameyn ku leh burooyinka.Waxay leedahay gaar gaar ah oo ka hortagga burooyinka iyo sunta hoose.Waxa loo isticmaalaa kiliinikada kansarka caloosha, kansarka mindhicirka iyo kansarka naasaha, oo leh heerka cafis ilaa 30% ama ka badan.
2. Dhexdhexaadinta dawooyinka.
3. Waa wakiilka antitumor, daawada hore ee fluorouracil (5-FU), taas oo loo beddelo fluorouracil lacag la'aan ah ficilka pyrimidine nucleoside phosphorylase ee unugyada burooyinka, sidaas darteed xakameynaya biosynthesis ee DNA iyo RNA ee unugyada burooyinka oo muujinaya saamaynta antitumor.Maaddaama hawsha enzymeni ay ka sarreyso unugyada burooyinka marka loo eego unugyada caadiga ah, beddelka 5-FU ee 5-FU ee unugyada burooyinka ayaa ah mid degdeg ah oo xulashada burooyinka.Waxaa loo isticmaalaa daawaynta kansarka naasaha, caloosha iyo malawadka waxayna leedahay suntu hooseyso.
