Dhawaan, cilmi-baarayaal ka socda Jaamacadda Georgia State University iyo Tufts University waxay ogaadeen in folic acid ay kicin karto kororka unugyada stem iyada oo loo marayo dhaqanka vitro iyo hababka xayawaanka, taas oo aan ku xirnayn doorkeeda fiitamiin ahaan, cilmi-baarista la xiriirta ayaa lagu daabacay joornaalka caalamiga ah. Unug korriinka.
Folic acid, haddii ay tahay fitamiin B dheeri ah ama folic acid dabiici ah oo laga helo cuntada, waxay lagama maarmaan u tahay shaqada caadiga ah ee dhammaan unugyada jidhka waxayna muhiim u tahay ka hortagga cilladaha korriinka ee dhallaanka cusub.Maqaalka, cilmi-baarayaashu waxay ugu horreyntii ogaadeen in dadka qaangaarka ah ee unugyada asliga ah lagu xakameyn karo arrin ka timid bannaanka jidhka xayawaanka, taas oo ah, folic acid ee bakteeriyada, sida noocyada nematodes sida Caenorhabditis elegans.
Cilmi-baaraha Edward Kipreos ayaa sheegay in daraasaddeennu ay muujinayso in unugyada tarma ee jeermiska ee caenorhabditis elegans loo qaybin karo kicinta folate ee cuntada bakteeriyada;Folic acid waa fiitamiin B lagama maarmaan ah, laakiin cilmi-baarayaashu waxay ogaadeen in awoodda folic acid ee gaarka ah si ay u kiciso unugyada jeermiska laga yaabo inaysan ku xirnaan doorkeeda fiitamiin B, taas oo muujin karta in folic acid ay si toos ah u ciyaarto doorka molecule signaling.
Folic acid ee dabiiciga ah waxay u egtahay inay ku timaado qaabab badan oo kiimiko ah, sida folic acid ee cuntada ama qaabka dheef-shiid kiimikaad ee folic acid ee jidhka bini'aadamka, iyo folic acid waxay sidoo kale ku jirtaa qaab weyn oo synthetic ah oo ku jira cuntooyinka la xoojiyay iyo fitamiinada dheeraadka ah.Folic acid waxa la helay sannadkii 1945-kii, tan iyo taariikhda la helay, cilmi-baarayaal badan ayaa daraasad badan ku sameeyay, waxaana hadda jira in ka badan 50,000 oo waraaqo cilmi-baaris ah oo la xidhiidha folic acid, laakiin daraasaddan ayaa ah mid gaar ah, sababtoo ah cilmi-baaristu waxay daaha ka qaadaysaa door cusub. ee folic acid, halkii doorka folic acid lagu muujiyey daraasadihii hore.
Folic acid ayaa hadda lagu daraa badarka Maraykanka iyo wadamada kale, iyo folic acid supplement waxay si weyn u dhimi kartaa dhalashada ilmaha leh cilladaha horumarinta tuubada neerfaha, laakiin doorka folic acid ee aan ku tiirsanayn fiitamiinada ayaa laga yaabaa inay ka caawiso inay bixiso dariiqa labaad jirka aadanaha.Maqaalka, cilmi-baarayaashu waxay ogaadeen in soo-dhoweeyaha gaarka ah ee loo yaqaan 'FOLR-1' uu lagama maarmaan u yahay inuu kiciyo koritaanka unugyada taranka taranka ee jirka Caenorhabditis elegans.
Isla mar ahaantaana, cilmi-baarayaashu waxay sidoo kale arkeen habka FOLR-1 reseptors kor u qaadaya burooyinka unugyada jeermiska ee caenorhabditis elegans, taas oo laga yaabo inay la mid tahay habka folic acid reseptors ee kicinaya horumarka kansarrada gaarka ah ee noolaha aadanaha;Dabcan, reseptors-yada waxaa laga yaabaa inaanay lagama maarmaan u ahayn qaadista folic acid ee unugyada si loogu isticmaalo fiitamiinada, laakiin waxay kicin karaan qaybta unugyada.Ugu dambeyntii, cilmi-baarayaashu waxay sheegeen in cilmi-baaristu ay sidoo kale na siin karto qalab cusub oo gacan ka geysanaya barashada noolaha moodada hidda-wadaha.
Waqtiga boostada: Mar-30-2022