oo Jumlada Shiinaha Soo saaraha Soo saaraha Thymidine Soo saaraha iyo Iibiyaha |LonGoChem
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Alaabta

Thymidine

Sharaxaad Gaaban:

Warbixin guud
Magaca badeecada: Thymidine
CAS No.: 50-89-5
EINECS lambarka gelitaanka: 200-070-4
qaacidada qaab dhismeedka:
Qaaciddada molecular: C10H14N2O5
Miisaanka molecular: 242.23


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Qaab-dhismeedka

3

Jireed
Muuqaalka: Budada Crystalline White
Midabka: Cadaan ilaa Ku dhawaad ​​Cadaan
Cufnaanta: 1.3129 (qiyaas adag)
Meesha dhalaalaysa: 186-188 °c ( shid)
Barta karkarinta:385.05°c (Qiyaas adag)
Dib-u-celinta:33 ° (c=1, 1mol/l Naoh)
Wareeg gaar ah:18.6º(c=3, H2o)
Xaalada Kaydinta:2-8°c
Sababta Aysiidhka (pka): pk1:9.79; pk2:12.85 (25°c)
Spinability: α]20/d +19±1°, C = 1% gudaha H2o
Ku milmay Biyaha dhexdiisa: milmay
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Xogta Badbaadada
Qaybta halista: Alaabo khatar ah maaha
Gaadiidka khatarta ah:
Qaybta baakadaha:

Codsiga
1.Waxa loo adeegsaday sidii dhexdhexaadiye dawo ah oo loogu talagalay isku-darka daawooyinka fayraska iyo ka-hortagga HIV-ga.
2. Sida dhexdhexaadka ah ee Zivdodine

Isticmaalka:
Thymidine waa deoxyribonucleoside ka kooban thymine sal.Thymidine waa nucleoside la sameeyay iyadoo lagu xirayo thymidine iyo D-ribose iyada oo loo marayo curaarta β-glycosidic.Thymidine waxaa loo isticmaalaa diyaarinta daawooyinka ka hortagga AIDS-ka (tusaale zidofuridine, stavudine) iyo isku dhafka daawooyinka fayraska.Waxa kale oo loo isticmaali karaa sidii dhexdhexaadka dawooyinka oo si toos ah loo dhoofin karaa.
Dhaqdhaqaaq noole:
Thymidine (Deoxythymidine,2'-Deoxythymidine,5-Methyldeoxyuridine,DThChemicalbookyd,NSC21548) waa pyrimidine nucleoside ka kooban thymine, saldhig pyrimidine ah oo ku dheggan deoxyribose sonkorta.Sida qayb ka mid ah DNA-da, thymine nucleosides waxay ku lammaaniyaan adenine ee helix labanlaaban oo DNA ah.


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