oo Jumladda Shiinaha ee Adenosine Soo-saare Soosaaraha iyo Iibiyaha |LonGoChem
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Alaabta

Adenosine

Sharaxaad Gaaban:

Magaca: Adenosine
Lambarka CAS: 58-61-7
EINECS lambarka gelitaanka: 200-389-9
Qaaciddada molecular: C10H13N5O4
Miisaanka molecular: 267.25


Faahfaahinta Alaabta

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Qaab-dhismeedka

1
Jireed

Muuqaal: crystalline cad ama budo crystalline off-caddaan
Cufnaanta: 2.08 g/cm³
Barta dhalaalka: 234 ilaa 236 ℃
Barta karkarinta: 676.3 ℃
dib u dhac: 1.907
Dhibicda Flash: 362.8 ℃

Xogta Badbaadada
Qaybta halista ah.
Lambarka Gaadiidka Alaabta Khatarta ah.
Qaybta xirxirida.

Codsiga
Adenosine waxaa loo isticmaalaa in lagu caawiyo soo celinta garaaca wadnaha caadiga ah ee dadka qaba xanuunada laxanka garaaca wadnaha qaarkood.
Adenosine sidoo kale waxaa loo isticmaalaa inta lagu jiro baaritaanka cadaadiska wadnaha.
Adenosine waxa kale oo loo isticmaali karaa ujeedooyin aan ku xusnayn hagaha daawaynta.

Adenosine, oo ah xarun ka kooban N-9 ee adenine oo ku xiran C-1 ee D-ribose by a β-glycosidic bond, waxay leedahay qaacidada kiimikada C10H13N5O4 iyo phosphate ester waa adenosine acid.Adenosine waa nucleoside endogenous ah oo ku faafta dhammaan unugyada bini'aadamka waxayna si toos ah u geli kartaa myocardium si ay u dhaliso adenosine acid by fosfooraska, taas oo ku lug leh dheef-shiid kiimikaadka tamarta myocardial, iyo sidoo kale ballaarinta xididdada halbowlayaasha iyo kordhinta socodka dhiigga.Waxaa loo isticmaalaa daawaynta tachycardia supraventricular.Adenosine waxay leedahay saameyn nafsiyeed oo ku saabsan habka wadnaha iyo xididada iyo nidaamyo kale oo badan oo muruqa ah.Adenosine waa dhexdhexaad muhiim ah oo loo isticmaalo isku dhafka adenosine triphosphate (ATP), adenine, adenosine acid, iyo adenosine asiaticum.
Sidoo kale waa wakiilka antiarrhythmic kaas oo u beddela tachycardia supraventricular paroxysmal una beddelo laxanka sinus.Waxa loo isticmaalaa supraventricular arrhythmias ee la xidhiidha atrioventricular.Daaweynta angina pectoris, wadnaxanuun myocardial, ku filnaansho la'aan, atherosclerosis, hypertension lagama maarmaanka ah, xanuunada cerebrovascular, post-stroke sequelae, atrophy muruqa horusocod ah, iwm Sidoo kale loo isticmaalo in daraasadaha biochemical.
Adenosine waa nucleoside-ka endogenous purine kaas oo hoos u dhigaya habka AV node, oo xannibaya dariiqa laablaabka qanjidhada AV, oo soo celisa laxanka sinuska caadiga ah ee bukaanada qaba tachycardia supraventricular paroxysmal (PSVT) (oo leh ama aan lahayn cudurka preexcitation syndrome).Adenosine waxaa si degdeg ah u qaada unugyada dhiigga cas, sidaas darteed waxay leedahay waqti gaaban oo ficil ah, oo leh nus-nolosha balaasmaha wax ka yar 10 s.Nooca ugu badan ee PSVT waa iyada oo loo marayo dariiqa dib-u-noqoshada, markaa adenosine waxay wax ku ool u tahay joojinta noocan ah arrhythmia.Marka ay jiraan kuwa aan ahayn atrial ama sinus node regressive arrhythmias (tusaale, atrial flutter, atrial fibrillation, atrial tachycardia, ventricular tachycardia), adenosine ma joojinayo iyaga, laakiin waxay soo saari kartaa xannibaad atrioventricular ama ventricular ku meel gaar ah, taas oo caawin karta samaynta ogaanshaha kala duwan.


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