Alaabta
2,6-Di-tert-butyl-4-methylpyridine
Qaab-dhismeedka
Muuqaalka: crystal acicular cad
Cufnaanta: 1,476 g/cm3
Meesha dhalaalka: 31-32 ℃
Barta karkarinta: 148-153 ℃ (12.6kPa)
Tusmada dib-u-celinta: N20/D 1.4763(lit.)
Barta toosh: 183 °F
Xaaladaha kaydinta: 2-8°C
Isku-dhafka aysiidhka (pKa): 6.88± 0.10 (La saadaaliyay)
Xogta Badbaadada
Waxaa iska leh xamuulka guud
Koodhka Kastamka: 2942000000
Heerka dhimista canshuurta dhoofinta (%): 13%
Codsiga
Dhexdhexaad-ka-soo-saarka dabiiciga ah, oo ah sterically xanibay, saldhig aan nucleophilic ahayn oo kala sooca Brnsted (protonic) iyo Lewis acids.Waxay sahlaysa beddelka tooska ah ee wax-soo-saarka sare ee aldehydes1 iyo ketones1,2 una beddelo triflate vinyl.
2,6-Di-tert-butyl-4-methylpyridine waa unug dabiici ah oo leh caanaha molecular C14H23N, oo ah dhexdhexaad muhiim ah oo ka mid ah isku-dhafka organic, oo inta badan loo isticmaalo dhexdhexaadiyeyaasha farmashiyaha, isku-darka organic, dareerayaasha organic, sidoo kale waxaa lagu dabaqi karaa wax soo saarka dheeha, sunta cayayaanka. wax soo saarka iyo udgoonka iwm.
Habka wax soo saarka
1. Samee 2,6 di-tert-butyl-4-methylbenzyl trifluoromethanesulfonate 100-mL oo saddexley ah oo lagu rakibay tuubo hordhac ah oo nitrogen ah, maro cadaadis joogto ah, bar kicinta korantada iyo qaboojiyaha barafka leh tuubo qalalan, ku dar 24.2 g (0.2 mol) oo ah trimethylethyl phthalide chloride iyo 3.7 g (0.05 mol) ee tert-butanol.Isku darka falcelinta waxaa lagu kululeeyay qubeyska saliidda ilaa 85 ° C.Kadib 15 g (0.1 mol) oo ah trifluoromethanesulfonic acid ayaa lagu daray in ka badan 15 daqiiqo.Dareen-celinta ayaa la sii waday 10 daqiiqo, iyo badeecada falcelinta brown khafiifka ah ayaa lagu qaboojiyey baraf baraf waxaana lagu shubay 100 ml oo ah ether qabow.Da'da bunni waa la sifeeyay oo la qalajiyey si loo helo 9.6 g (54%) ee milixda dib u dhacday.(Sidiifinta looma baahna: tallaabada xigta ee diyaarinta, laba jeer ka samee chloroform ilaa kaarboon tetrachloride 3:1) ilaa kiristaalo irbad la mid ah oo aan midab lahayn.
2. Diyaarinta 2,6-Di-tert-butyl-4-methyl-vizine hoosteeda, ka joojinta 10 g (0.028 mol) ee milixda cayriin ee vizine ee 200 mL ee 95% ethanol la qaboojiyey ilaa 60 ° C lagu daray hal mar 100 mL oo ah ammonia uruursan oo la qaboojiyey ilaa 60°C ee galaas 1-litir ah oo beer ah.Dareen-celinta ayaa lagu sii waday 60 ° C 30 daqiiqo iyo 40 ° C ilaa 2 saacadood, inta lagu jiro wakhtigaas ayaa la kala diray joojinta.Kadibna, isku darka falcelinta ayaa lagu shubay 500 ml oo ah 2% sodium hydroxide xal si tartiib ah u diirran heerkulka qolka.La soo saaray .4-100 ml oo pentane ah, soosaaryo la isku daray, 25 ml oo ah xal sodium chloride saturated ah oo la dhaqay, 100 ml oo ah feejignaanta uumiga rotary pentane.
